Article
Intrinsic epigenetic state of primary osteosarcoma drives metastasis
2023-11-13
Abstract excerpt
Osteosarcoma (OS) is the most common primary malignant bone tumor affecting the pediatric population with high potential to metastasize to distal sites, most commonly the lung. Insights into defining molecular features contributing to metastatic potential are lacking. We have mapped the active chromatin landscapes of OS tumors by integrating histone H3 lysine acetylated chromatin (H3K27ac) profiles (n=13), chromat...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- e20d65fc-c3d9-5940-857b-2a9ab76cb4c2
- DOI
- 10.1101/2023.11.09.566446