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Integrated single-cell analysis reveals heterogeneity and therapeutic insights in osteosarcoma

18 Nov 2024

Abstract excerpt

Osteosarcoma (OSA) is a primary bone malignancy characterized by its aggressive nature and high propensity for metastasis. Despite advancements in multimodal therapies, the clinical outcomes for OSA patients remain suboptimal, necessitating deeper molecular insights for improved therapeutic strategies. Here, we employed single-cell RNA sequencing (scRNA-seq) to elucidate the cellular heterogeneity and...

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Cancer Genomics and Diagnostics
Sarcoma Diagnosis and Treatment
Single-cell and spatial transcriptomics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39556142
DOI: 10.1007/s12672-024-01523-x

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