Article
Sustained Co-evolution in a Stochastic Model of the Cancer-Immune Interaction
2019-06-23
Abstract excerpt
<h4>Summary</h4> The dynamical interaction between a growing cancer population and the adaptive immune system generates diverse evolutionary trajectories which ultimately result in tumor clearance or immune escape. Here, we create a simple mathematical model coupling T-cell recognition with an evolving cancer population which may randomly produce evasive subclones, imparting transient protection against the effec...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 76ac3fb3-58c7-59c7-9aaf-db8431bd9cad
- DOI
- 10.1101/679746