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Article

A transcriptomic atlas of the human brain reveals genetically determined aspects of neuropsychiatric health.

American journal of human genetics - 8 Aug 2024

Bledsoe Xavier, Gamazon Eric R

Abstract excerpt

Regulation of gene expression is a vital component of neurological homeostasis. Cataloging the consequences of endogenous gene expression on the physical structure and connectivity of the brain offers a means of unifying trait-associated genetic variation with trait-associated neurological features. We perform tissue-specific transcriptome-wide association studies (TWASs) on over 3,400 neuroimaging phenotypes in...

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Identifiers

PMID: 38925120
DOI: 10.1016/j.ajhg.2024.06.002
PMCID: PMC11339608

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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