Article

Impact of single nucleotide variants and nutritional status on population pharmacokinetics of Doxorubicin, and its effect on cardiotoxicity in children with leukemia.

2022-06-23

Abstract excerpt

Doxorubicin (DOX) is a highly useful antineoplastic in the treatment of different types of cancer; however, its use is limited due to its wide variability between patients in their susceptibility to the cardiotoxic effects of anthracyclines. <h4>Purpose: </h4> The aim of this study was to determine the effect of single nucleotide variants (SNV) and the nutritional status on the population pharmacokinetics of DOX,...

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Literature Corpus work: e19f8b4d-f642-5d4c-8eef-4eec8a5c653e
DOI: 10.22541/au.165544430.02844470/v2

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Impact of single nucleotide variants and nutritional status on population pharmacokinetics of Doxorubicin, and its effect on cardiotoxicity in children with leukemia.DOI 10.22541/au.165544430.02844470/v2Read

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