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Article

Pharmacogenetics of genes across the doxorubicin pathway.

Expert opinion on drug metabolism & toxicology - 1 Oct 2011

Jamieson David, Boddy Alan V

Abstract excerpt

INTRODUCTION: A large number of genetic polymorphisms have been reported in the genes that mediate the metabolism, transport and pharmacological activity of doxorubicin. The clinical significance of these is still undergoing evaluation. AREAS COVERED: Doxorubicin is a widely used anticancer drug in the treatment of solid tumors and leukemias. It is a drug characterized by inter-individual variation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21919804
DOI: 10.1517/17425255.2011.610180

Genes

ABCB1
CRB1
CRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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