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Article

ABCC1 polymorphisms in anthracycline-induced cardiotoxicity in childhood acute lymphoblastic leukaemia.

Cell biology international - 1 Jan 2012

Semsei Agnes F, Erdelyi Daniel J, Ungvari Ildiko, Csagoly Edit, Hegyi Marta Z, Kiszel Petra S, Lautner-Csorba Orsolya, Szabolcs Judit, Masat Peter, Fekete Gyorgy, Falus Andras, Szalai Csaba, Kovacs Gabor T

Abstract excerpt

Anthracyclines are potent cytostatic drugs, the correct dosage being critical to avoid possible cardiac side effects. ABCC1 [ATP-binding cassette, sub-family C, member 1; also denoted as MRP1 (multidrug resistance-associated protein 1)] is expressed in the heart and takes part in the detoxification and protection of cells from the toxic effects of xenobiotics, including anthracyclines. Our objective was to search...

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Source

Identifiers

PMID: 21929509
DOI: 10.1042/CBI20110264

Genes

ABCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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