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Article

Proteostasis and longevity: when does aging really begin?

2014-02-03

Abstract excerpt

Aging is a complex process regulated by multiple cellular pathways, including the proteostasis network. The proteostasis network consists of molecular chaperones, stress-response transcription factors, and protein degradation machines that sense and respond to proteotoxic stress and protein misfolding to ensure cell viability. A loss of proteostasis is associated with aging and age-related disorders in diverse mod...

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Identifiers and source

Literature Corpus work
e1328c4a-d76c-5a4b-8d3b-d14a2eb0a603
DOI
10.12703/p6-07
Open publication

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Proteostasis and longevity: when does aging really begin?DOI 10.12703/p6-07
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