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Cellular Homeostasis and Aging

7 Apr 2016

Abstract excerpt

Aging and longevity are controlled by a multiplicity of molecular and cellular signaling events that interface with environmental factors to maintain cellular homeostasis. Modulation of these pathways to extend life span, including insulin-like signaling and the response to dietary restriction, identified the cellular machineries and networks of protein homeostasis (proteostasis) and stress resistance pathways as...

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PMID: 27050288
DOI: 10.1146/annurev-biochem-011116-110806

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