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Protein homeostasis in aging and cancer

16 Feb 2023

Abstract excerpt

Aging is a major risk factor for cancer development. As dysfunction in protein homeostasis, or proteostasis, is a universal hallmark of both the aging process and cancer, a comprehensive understanding of the proteostasis system and its roles in aging and cancer will shed new light on how we can improve health and quality of life for older individuals. In this review, we summarize the regulatory mechanisms of...

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Autophagy in Disease and Therapy
Endoplasmic Reticulum Stress and Disease
Ubiquitin and proteasome pathways

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36875752
DOI: 10.3389/fcell.2023.1143532

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