Article

Organ-specific electrophile responsivity mapping in live <i>C. elegans</i>

2024-09-28

Abstract excerpt

Proximity labeling technologies are limited to indexing localized protein residents. Such data— although valuable—cannot inform on small-molecule responsivity of local residents. We here bridge this gap by demonstrating in live C. elegans how electrophile-sensing propensity in specific organs can be quantitatively mapped and ranked. Using this method, >70% of tissue-specific responders exhibit novel responsivity,...

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Literature Corpus work: e0fe3ae6-254c-5c91-b442-ed5ac65703c7
DOI: 10.1101/2024.09.27.615266

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