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Meiotic cohesin paralogs govern cell survival by exhibiting flexibility in partner choice

2026-03-30

Abstract excerpt

Erroneous loading of the ring-shaped cohesin complex, especially at centromeres, cause chromosomal segregation defects in both mitosis and meiosis. Mitotic cohesin subunits of this complex, either get replaced or co-exist with their meiotic paralogs during meiosis and also in certain cancers. However, it is unclear whether meiotic paralogs can partner mitotic subunits to form hybrid complexes in somatic cells and...

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Literature Corpus work
e0f88469-48a0-5408-b23e-4f40b3c89fd0
DOI
10.64898/2026.03.27.714714
Open publication

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Meiotic cohesin paralogs govern cell survival by exhibiting flexibility in partner choiceDOI 10.64898/2026.03.27.714714
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