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Article

Coupling meiotic chromosome axis integrity to recombination.

Genes & development - 15 Mar 2008

Storlazzi Aurora, Tesse Sophie, Ruprich-Robert Gwenael, Gargano Silvana, Pöggeler Stefanie, Kleckner Nancy, Zickler Denise

Abstract excerpt

During meiosis, DNA events of recombination occur in direct physical association with underlying chromosome axes. Meiotic cohesin Rec8 and cohesin-associated Spo76/Pds5 are prominent axis components. Two observations indicate that recombination complexes can direct the local destabilization of underlying chromosome axes. First, in the absence of Rec8, Spo76/Pds5 is lost locally at sites of late-persisting Msh4...

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Identifiers

PMID: 18347098
DOI: 10.1101/gad.459308
PMCID: PMC2275432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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