Article

Ly6C defines a subset of memory-like CD27 <sup>+</sup> γδ T cells with inducible cancer-killing function

2020-09-08

Abstract excerpt

<h4>ABSTRACT</h4> In mice, IFNγ-producing γδ T cells that express the co-stimulatory molecule, CD27, play a critical role in host defence and anti-tumour immunity. However, their phenotypic diversity, composition in peripheral and secondary lymphoid organs, similarity to αβ T cells as well as homology with human γδ T cells is poorly understood. Here, using single cell RNA sequencing, we show that CD27 + γδ T cel...

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Literature Corpus work: e0d0f9db-e237-5a90-9a08-f4d779a75e45
DOI: 10.1101/2020.09.08.287854

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