Article

IL-27 maintains cytotoxic Ly6C <sup>+</sup> γδ T cells that arise from immature precursors

2023-10-30

Abstract excerpt

<h4>ABSTRACT</h4> In mice, γδ T cells that express the co-stimulatory molecule, CD27, are committed to the IFNγ-producing lineage in the thymus, and in the periphery, these cells play a critical role in host defence and anti-tumor immunity. Unlike αβ T cells that rely on MHC-presented peptides to drive their terminal differentiation, it is unclear whether MHC-unrestricted γδ T cells undergo further functional mat...

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Literature Corpus work: 8a7b1fc2-ce4d-59cf-9b34-82355c65ac46
DOI: 10.1101/2023.10.26.564114

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