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Transcriptome Analysis and Single-Cell Sequencing Analysis Reveal the Prognostic Value and Immune Landscapes of CD276 in Pan-Cancer and Clinical Validation in Glioblastoma

2022-11-15

Abstract excerpt

<h4>Background: </h4> CD276, also known as B7-H3, is one of the most important immune checkpoints of CD28 and B7 families, and its abnormal expression is closely associated with cancers. It has been discovered that CD276 can inhibit the function of T cells, which may become a promising immunotherapy target for cancers. Methods Since there are few systematic studies on CD276 in cancers, this study used single-cell...

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Literature Corpus work: a144208b-8868-51a9-8f8a-47037cd3f441
DOI: 10.21203/rs.3.rs-2183619/v1

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