Article

A pan-cancer gamma delta T cell repertoire

2024-07-22

Abstract excerpt

<h4>SUMMARY</h4> This report presents the largest collection of gamma-delta T cell receptor (γδ TCR) reads in human cancer to date, analyzing about 11,000 patient tumor samples across 33 cancer types using the TRUST4 algorithm. Despite γδ T cells being a small fraction of the T cell population, they play a key role in both innate and adaptive immunity. Our comprehensive analysis reveals their significant presence...

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Literature Corpus work: 00f599ed-8343-5660-88ed-daa7d5809fe6
DOI: 10.1101/2024.07.18.604205

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