Article

Cognitive hyperplasticity drives insomnia

2024-07-18

Abstract excerpt

Sleep is vital for maintenance of cognitive functions and lifespan across the animal kingdom. Here, we report our surprising findings that insomniac ( inc ) Drosophila short sleep mutants, which lack a crucial adaptor protein for the autism-associated Cullin-3 ubiquitin ligase, exhibited excessive olfactory memory. Through a genetic modifier screen, we find that a mild attenuation of Protein Kinase A (PKA) signa...

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Literature Corpus work: e0cd88b8-a01a-560a-866c-15eb616b7e5d
DOI: 10.1101/2024.07.16.603670

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