Article

Association between lipid-lowering agents with intervertebral disc degeneration, sciatica and low back pain: A drug-targeted Mendelian randomized study and cross-sectional observation

2024-08-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Abnormal lipid metabolism is linked to intervertebral disc degeneration (IVDD), sciatica, and low back pain (LBP), but it remains unclear whethertargeted interventions can prevent these issues. This study investigated the causal effectsof lipid-lowering drug use on IVDD, sciatica, and LBP development. <bold>Methods</bold>: Single-nucleotide polymorphisms (SNPs)...

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Literature Corpus work: e0acab8f-d3f5-507e-8ade-e02955fe8410
DOI: 10.21203/rs.3.rs-4750592/v1

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