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Mendelian Randomization and Drug Repurposing Analysis Identifies APOE as a Potential Therapeutic Target for Low Back Pain

2025-09-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Low back pain (LBP) is a prevalent chronic pain syndrome primarily driven by spinal degeneration, causing persistent disability and reduced quality of life. Despite available interventions, identifying novel therapeutic targets remains imperative for modifying disease progression. <bold>Methods</bold>: We performed Mendelian randomization (MR) analyses integrati...

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Literature Corpus work
241dc956-ba53-5be5-b1e0-dcd2e0b68fd7
DOI
10.21203/rs.3.rs-7587626/v1
Open publication

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Mendelian Randomization and Drug Repurposing Analysis Identifies APOE as a Potential Therapeutic Target for Low Back PainDOI 10.21203/rs.3.rs-7587626/v1
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