Article

Interparental Gene Conversion in General Population: A Novel Mechanism For Loss of Heterozygosity

2024-12-07

Abstract excerpt

Gene conversion is a process in which genetic material from a donor sequence is unidirectionally copied to an acceptor sequence during the homologous recombination repair of a DNA double-strand break. Although gene conversion has been widely studied in the context of meiosis, hereditary diseases, and cancer development, gene conversion between parental homologs in the zygotes remains controversial. Here, we develo...

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Literature Corpus work: e0a99786-cbaa-5624-8350-d76f0664f1eb
DOI: 10.1101/2024.12.05.626979

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