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Article

Interlocus gene conversion explains at least 2.7% of single nucleotide variants in human segmental duplications.

BMC genomics - 16 Jun 2015

Dumont Beth L

Abstract excerpt

BACKGROUND: Interlocus gene conversion (IGC) is a recombination-based mechanism that results in the unidirectional transfer of short stretches of sequence between paralogous loci. Although IGC is a well-established mechanism of human disease, the extent to which this mutagenic process has shaped overall patterns of segregating variation in multi-copy regions of the human genome remains unknown. One expected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Segmental Duplications, Genomic

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Identifiers

PMID: 26077037
DOI: 10.1186/s12864-015-1681-3
PMCID: PMC4467073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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