Article

Recombination impacts damaging and disease mutation accumulation in human populations

2014-06-08

Abstract excerpt

Many decades of theory have demonstrated that in non-recombining systems, slightly deleterious mutations accumulate non-reversibly 1 , potentially driving the extinction of many asexual species. Non-recombining chromosomes in sexual organisms are thought to have degenerated in a similar fashion 2 , however it is not clear the extent to which these processes operate along recombining chromosomes with highly varia...

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Literature Corpus work: 69e8d974-c859-5309-a031-fa4a2be7b7a1
DOI: 10.1101/006064

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