Article

Studies on DNA—protein interactions in the upstream regulatory region of the human #epsilon#—globin gene promoter

1996-01-01

Abstract excerpt

The erythroid- and developmental stage-specific expression of the human #epsilon#-globin gene is controlled,in part,by the 5'-flanking DNA sequence of this gene.In the present study,we have used DNA-protein binding assays to identify trans-acting factors which regulate the temporal expression of the human #epsilon#-globin gene during development.Using gel mobility shift assays and DNaseI footprinting assays,a nucl...

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Literature Corpus work: e0447d32-0da1-5a1c-9e05-1b51dc596676
DOI: 10.1038/cr.1996.12

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