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Article

Characterization of the human beta-globin downstream promoter region.

Nucleic acids research - 15 Feb 2003

Leach Kelly M, Vieira Karen F, Kang Sung-Hae Lee, Aslanian Ara, Teichmann Martin, Roeder Robert G, Bungert Jörg

Abstract excerpt

The human beta-globin gene is abundantly expressed specifically in adult erythroid cells. Stage-specific transcription is regulated principally by promoter proximal cis-regulatory elements. The basal promoter contains a non-canonical TATA-like motif as well as an initiator element. These two elements have been shown to interact with the TFII-D complex. Here we show that in addition to the TATA and initiator...

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Source

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Identifiers

PMID: 12582249
DOI: 10.1093/nar/gkg209
PMCID: PMC150227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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