Article
Emr1 regulates the number of foci of the endoplasmic reticulum-mitochondria encounter structure complex.
Nature communications - 22 Jan 2021
Rasul Faiz, Zheng Fan, Dong Fenfen, He Jiajia, Liu Ling, Liu Wenyue, Cheema Javairia Yousuf, Wei Wenfan, Fu Chuanhai
Abstract excerpt
The endoplasmic reticulum-mitochondria encounter structure (ERMES) complex creates contact sites between the endoplasmic reticulum and mitochondria, playing crucial roles in interorganelle communication, mitochondrial fission, mtDNA inheritance, lipid transfer, and autophagy. The mechanism regulating the number of ERMES foci within the cell remains unclear. Here, we demonstrate that the mitochondrial membrane...
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