Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endoplasmic reticulum-mitochondria junction is required for iron homeostasis.

The Journal of biological chemistry - 11 Aug 2017

Xue Yong, Schmollinger Stefan, Attar Narsis, Campos Oscar A, Vogelauer Maria, Carey Michael F, Merchant Sabeeha S, Kurdistani Siavash K

Abstract excerpt

The endoplasmic reticulum (ER)-mitochondria encounter structure (ERMES) is a protein complex that physically tethers the two organelles to each other and creates the physical basis for communication between them. ERMES functions in lipid exchange between the ER and mitochondria, protein import into mitochondria, and maintenance of mitochondrial morphology and genome. Here, we report that ERMES is also required...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endoplasmic Reticulum
Share to Energy Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Homeostasis

Share to RNA, Fungal

Share to Sequence Analysis, RNA

Share to Spectrophotometry, Atomic

Source

Open in PubMed Open full text

Identifiers

PMID: 28637866
DOI: 10.1074/jbc.M117.784249
PMCID: PMC5555183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endoplasmic reticulum-mitochondria junction is required for iron homeostasis.PMID 28637866Read ↗

ESYT1 tethers the endoplasmic reticulum to mitochondria and is required for mitochondrial lipid and calcium homeostasisSemantic proximity Read ↗

ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.Semantic proximity Read ↗

Emr1 regulates the number of foci of the endoplasmic reticulum-mitochondria encounter structure complex.Semantic proximity Read ↗

ER-mitochondria contacts promote mitochondrial-derived compartment biogenesis.Semantic proximity Read ↗

ER-shaping proteins facilitate lipid exchange between the ER and mitochondria in S. cerevisiae.Semantic proximity Read ↗

Gem1 and ERMES do not directly affect phosphatidylserine transport from ER to mitochondria or mitochondrial inheritance.Semantic proximity Read ↗

Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease.Semantic proximity Read ↗

Iron-sulfur cluster biosynthesis and trafficking - impact on human disease conditions.Semantic proximity Read ↗

The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum.Semantic proximity Read ↗

Mitochondrial ER Contacts Are Crucial for Mitophagy in YeastSemantic proximity Read ↗

Vmp1, Vps13D, and Marf/Mfn2 function in a conserved pathway to regulate mitochondria and ER contact in development and diseaseSemantic proximity Read ↗

Iron-sulfur-protein biogenesis in eukaryotes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.