Pro-inflammatory secretome from intestinal epithelium recruits regulatory T cells for barrier defence

Abstract excerpt

<title>Abstract</title> <p>Resolution of inflammation, including of colitis, requires carefully coordinated communication between different tissues. While the role of immune cells in colitis is well established, less is known about epithelial communication to its microenvironment. Most secreted factors that comprise cellular communication are directly regulated by the transcription factor NF-κB. However, which tr...

Topics

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• Acute-Phase Proteins
• Colitis
• Colon
• Dextran Sulfate
• Helicobacter pylori-related gastroenterology studies
• Inflammatory Bowel Disease
• NF-κB Signaling Pathways
• RNA-Seq

Identifiers and source

Literature Corpus work

e03897c8-c107-50a0-9fe2-36ce5c658bc1

DOI

10.21203/rs.3.rs-5431057/v1