Article

Transcriptomic profiling of lymphocytic colitis highlights distinct diarrhoeal pathomechanisms

2023-03-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> The pathobiology of the non-destructive inflammatory bowel disease (IBD) lymphocytic colitis (LC) is poorly understood. Our aim was to define a LC-specific transcriptome to gain insight into LC pathology, identify genetic signatures uniquely linked to LC, and uncover potentially druggable disease pathways. <h4>Methods</h4> We performed whole mucosa bulk RNA-sequencing...

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Literature Corpus work: b3995ffe-ac76-576a-8eee-d9158f7c670b
DOI: 10.1101/2023.03.14.23287226

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