Article

p38 blockade reverses the immune suppressive tumor microenvironment in metastatic breast cancer

2025-10-29

Abstract excerpt

<title>Abstract</title> <p> Metastatic breast cancer (MBC) is a life-threatening disease with limited therapeutic options. The immune suppressive tumor microenvironment (TME) limits the potency of the antitumor immune response and facilitates disease progression and metastasis. Our current study demonstrates that p38α is a druggable target in the TME that regulates the outcome of the immune-tumor interaction. Th...

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Literature Corpus work: e036c508-eff2-5739-979f-87f7700b57a7
DOI: 10.21203/rs.3.rs-7151795/v1

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