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A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancer

2022-01-05

Abstract excerpt

<title>Abstract</title> <p>Immune checkpoint therapy in breast cancer remains restricted to triple negative patients, and long-term clinical benefit is rare. The primary aim of immune checkpoint blockade is to prevent or reverse exhausted T cell states, but the causes and implications of T cell exhaustion in breast tumors are not well understood. Here, we used single-cell transcriptomics combined with imaging mas...

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Literature Corpus work
30e6d2f0-4521-5844-a5a9-bfd2a79f65d6
DOI
10.21203/rs.3.rs-1155834/v1
Open publication

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A comprehensive single-cell map of T cell exhaustion-associated immune environments in human breast cancerDOI 10.21203/rs.3.rs-1155834/v1
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