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Single-cell RNA sequencing reveals immunosuppressive pathways associated with metastatic breast cancer

2024-09-26

Abstract excerpt

Metastatic breast cancer remains largely incurable, and the mechanisms underlying the transition from primary to metastatic breast cancer remain elusive. We analyzed the complex landscape of primary and metastatic breast cancer using scRNA-seq data from twenty-three female patients with either primary or metastatic disease to elucidate the genetic and molecular mechanisms underlying changes in the metastatic tumor...

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Literature Corpus work
7387b790-9952-51bf-a48f-6d959cd68072
DOI
10.1101/2024.09.25.24314388
Open publication

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Single-cell RNA sequencing reveals immunosuppressive pathways associated with metastatic breast cancerDOI 10.1101/2024.09.25.24314388
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