Article

Spinal cord pathology in a Dravet Syndrome mouse model

2023-09-22

Abstract excerpt

<h4>Summary</h4> <h4>Objectives</h4> Dravet syndrome is a severe epileptic encephalopathy that begins in early childhood. More than 80% of patients with Dravet syndrome exhibit a haploinsufficiency in SCN1A , which encodes the voltage-gated sodium ion channel Na V 1.1. The epilepsy is believed be caused by specific deficit of SCN1A in inhibitory interneurons of the hippocampus. However, the aetiology of other...

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Literature Corpus work: d08ea7b6-4b20-5b49-8c5f-9c36afb84318
DOI: 10.1101/2023.09.22.558962

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