Article

Astrocytes regulate locomotion by orchestrating neuronal rhythmicity in the spinal network via potassium clearance

2022-07-07

Abstract excerpt

<h4> S ummary </h4> Neuronal rhythmogenesis in the spinal cord is correlated with variations in extracellular K + levels ([K + ] e ). Astrocytes play important role in[K + ] e homeostasis and compute neuronal information. Yet it is unclear how neuronal oscillations are regulated by astrocytic K + homeostasis. Here we identify the astrocytic inward-rectifying K + channel Kir4.1 (a.k.a. Kcnj10 ) as a key...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 843b0004-cfaa-521f-93fe-be09cc9fcd49
DOI: 10.1101/2022.07.07.498974

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Astrocytes regulate locomotion by orchestrating neuronal rhythmicity in the spinal network via potassium clearanceDOI 10.1101/2022.07.07.498974Read

Functional contribution of astrocytic Kir4.1 channels to spasticity after spinal cord injurySemantic proximity Read

Ca <sup>2+</sup> signaling in astrocytes is sleep-wake state specific and modulates sleepSemantic proximity Read

Functional expression of Kir4.1 channels in spinal cord astrocytes.Semantic proximity Read

Astrocytes control UP state and slow oscillation periodicity in human cortical networksSemantic proximity Read

Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling.Semantic proximity Read

Long-term plasticity of astrocytic phenotypes and their control by neurons in health and disease.Semantic proximity Read

Distinct Ca <sup>2+</sup> signatures of leptomeningeal fibroblast subgroups in awake mouse brains in health and inflammationSemantic proximity Read

Astrocytic Ryk signaling coordinates scarring and wound healing after spinal cord injurySemantic proximity Read

Distinct Ca2+ signatures of leptomeningeal fibroblast subgroups in awake mouse brains in health and inflammationSemantic proximity Read

Motor-Skill Learning Is Dependent on Astrocytic Activity.Semantic proximity Read

Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cells.Semantic proximity Read

Ionic Mechanisms Underlying Bistability in Spinal Motoneurons: Insights from a Computational ModelSemantic proximity Read