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Enhancer-directed gene delivery for digit regeneration based on conserved epidermal factors

2025-12-02

Abstract excerpt

Limb loss remains a significant clinical challenge, but regenerative medicine approaches such as gene therapy offer a promising strategy to trigger endogenous regeneration programs. Optimal vector configurations and molecular targets for appendicular skeletal repair are not well defined. Here, we leveraged insights from species with a high endogenous capacity for appendage regeneration to design an enhancer-direct...

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Literature Corpus work
e00e913a-4c7d-5974-8bad-63a27055ef3e
DOI
10.64898/2025.12.01.691633
Open publication

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Enhancer-directed gene delivery for digit regeneration based on conserved epidermal factorsDOI 10.64898/2025.12.01.691633
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