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Initiation of limb regeneration: The critical steps for regenerative capacity

6 Nov 2007

Abstract excerpt

While urodele amphibians (newts and salamanders) can regenerate limbs as adults, other tetrapods (reptiles, birds and mammals) cannot and just undergo wound healing. In adult mammals such as mice and humans, the wound heals and a scar is formed after injury, while wound healing is completed without scarring in an embryonic mouse. Completion of regeneration and wound healing takes a long time in regenerative and...

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PMID: 17986260
DOI: 10.1111/j.1440-169x.2007.00973.x

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