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Article

Limb regeneration in higher vertebrates: Developing a roadmap

1 Nov 2005

Abstract excerpt

We review what is known about amphibian limb regeneration from the prospective of developing strategies for the induction of regeneration in adult mammals. Prominent in urodele amphibian limb regeneration is the formation of a blastema of undifferentiated cells that goes on to reform the limb. The blastema shares many properties with the developing limb bud; thus, the outgrowth phase of regeneration can be...

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PMID: 16308860
DOI: 10.1002/ar.b.20082

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