Article

AXL is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

2020-07-07

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDA), a leading cause of cancer-related death in the US, has a high metastatic rate and is associated with persistent immune suppression. AXL, a member of the TAM (TYRO3, AXL, MERTK) receptor tyrosine kinase family, has been identified as a driver of metastasis and immune suppression in multiple cancer types. Here we use single cell RNA sequencing to reveal that AXL is expressed h...

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Literature Corpus work: e002b020-1adf-5427-8150-3c87394e6e30
DOI: 10.1101/2020.07.06.190363

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