Article

Single-cell RNA sequencing reveals microenvironment context-specific routes for epithelial-mesenchymal transition in pancreas cancer cells

2023-05-31

Abstract excerpt

<h4>ABSTRACT</h4> In the PDAC tumor microenvironment, multiple factors initiate the epithelial-mesenchymal transition (EMT) that occurs heterogeneously among transformed ductal cells, but it is unclear if different drivers promote EMT through common or distinct signaling pathways. Here, we use single-cell RNA sequencing (scRNA-seq) to identify the transcriptional basis for EMT in pancreas cancer cells in response...

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Literature Corpus work: a786d079-06be-5d07-9189-5c5b1f7049ce
DOI: 10.1101/2023.05.30.542969

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