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Article

Untargeted metabolome- and transcriptome-wide association study identifies causal genes modulating metabolite concentrations in urine

2020-05-25

Abstract excerpt

<h4>Summary</h4> In this study we investigate the results of a metabolome- and transcriptome-wide association study to identify genes influencing the human metabolome. We used RNAseq data from lymphoblastoid cell lines (LCLs) derived from 555 Caucasian individuals to characterize their transcriptome. As for the metabolome we took an untargeted approach using binned features from 1 H nuclear magnetic resonance sp...

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Literature Corpus work
e0018c03-353c-5b3e-b72f-3f95f1568d6a
DOI
10.1101/2020.05.22.110197
Open publication

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Untargeted metabolome- and transcriptome-wide association study identifies causal genes modulating metabolite concentrations in urineDOI 10.1101/2020.05.22.110197
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