Article

Serum Amyloid A proteins reduce bone mass during mycobacterial infections

2022-10-26

Abstract excerpt

Osteopenia has been associated to several inflammatory conditions, including mycobacterial infections. How mycobacteria cause bone loss remains elusive, but direct bone infection may not be required. Using genetically engineered mice and morphometric, transcriptomic and functional analyses, we found that infection with Mycobacterium avium impacts bone turnover by decreasing bone formation and increasing bone reso...

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Literature Corpus work: dff73f2d-e14f-5efa-9170-331e985e7f92
DOI: 10.1101/2022.10.24.513637

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