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Article

Induction of protective interferon-β responses in murine osteoblasts following Staphylococcus aureus infection

2 Dec 2022

Abstract excerpt

Introduction The refractory and recurrent nature of chronic staphylococcal osteomyelitis may be due, at least in part, to the ability of Staphylococcus aureus to invade and persist within bone-forming osteoblasts. However, osteoblasts are now recognized to respond to S. aureus infection and produce numerous immune mediators and bone regulatory factors that can shape the host response. Type I interferons (IFNs)...

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PMID: 36532419
DOI: 10.3389/fmicb.2022.1066237

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