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Article

Mycobacterium tuberculosis-Induced Maternal Immune Activation Promotes Autism-Like Phenotype in Infected Mice Offspring.

International journal of environmental research and public health - 23 Apr 2021

Manjeese Wadzanai, Mvubu Nontobeko E, Steyn Adrie J C, Mpofana Thabisile

Abstract excerpt

The maternal system's exposure to pathogens during pregnancy influences fetal brain development causing a persistent inflammation characterized by elevated pro-inflammatory cytokine levels in offspring. Mycobacterium tuberculosis (Mtb) is a global pathogen that causes tuberculosis, a pandemic responsible for health and economic burdens. Although it is known that maternal infections increase the risk of autism...

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Identifiers

PMID: 33922864
DOI: 10.3390/ijerph18094513
PMCID: PMC8122996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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