Article

WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm

2024-10-12

Abstract excerpt

Embryonic stem cell research has uncovered different requirements for WNT/β-catenin signalling in human naïve pluripotent cells compared to the mouse paradigm. It is therefore important to study WNT/β-catenin signalling directly in models of early human development. Since TCF/LEF factors mediate the regulation of target genes downstream of WNT/β-catenin signalling, we studied the expression and protein localisatio...

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Literature Corpus work: dfc85d02-fb3b-53d0-b8f8-5b78fbb18896
DOI: 10.1101/2024.10.08.617210

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WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigmDOI 10.1101/2024.10.08.617210Read

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