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Unravelling immune microenvironment features underlying tumor progression in the single-cell era

22 Apr 2024

Abstract excerpt

The relationship between the immune cell and tumor occurrence and progression remains unclear. Profiling alterations in the tumor immune microenvironment (TIME) at high resolution is crucial to identify factors influencing cancer progression and enhance the effectiveness of immunotherapy. However, traditional sequencing methods, including bulk RNA sequencing, exhibit varying degrees of masking the cellular...

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PMID: 38649887
DOI: 10.1186/s12935-024-03335-z

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