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DLPFC transcriptome defines two molecular subtypes of schizophrenia

9 May 2019

Abstract excerpt

Abstract Little is known about the molecular pathogenesis of schizophrenia, possibly because of unrecognized heterogeneity in diagnosed patient populations. We analyzed gene expression data collected from the dorsolateral prefrontal cortex (DLPFC) of post-mortem frozen brains of 189 adult diagnosed schizophrenics and 206 matched controls. Transcripts from 633 genes are differentially expressed in the DLPFC of...

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PMID: 31073119
DOI: 10.1038/s41398-019-0472-z

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