Article

Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn’s disease

2020-11-24

Abstract excerpt

<h4>Background and Aims</h4> The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn’s disease (CD) and non-inflammatory bowel disease (non-IBD) controls. We hypothesized that the colonic expression levels of ACE2 impacts CD course. <h4>Methods</h4> We examined the expression of colon ACE2 using RNA-s...

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Literature Corpus work: df5dedd3-a113-5f73-a494-b8abc50cd963
DOI: 10.1101/2020.11.24.396382

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