Article

Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn’s Disease

2021-02-03

Abstract excerpt

<h4>Background and Aims: </h4> The host receptor for SARS-CoV-2, angiotensin-converting enzyme 2 (ACE2), is highly expressed in small intestine. Our aim was to study colonic ACE2 expression in Crohn's disease (CD) and non-inflammatory bowel disease (non-IBD) controls. We hypothesized that the colonic expression levels of ACE2 impacts CD course. <h4>Methods: </h4>: We examined the expression of colon ACE2 using RNA...

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Literature Corpus work: c80b1830-8d11-5155-8df2-f230c18a8f25
DOI: 10.21203/rs.3.rs-150844/v1

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