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Effects of ACE2 and Co-factors on the Mechanism of SARS-CoV-2 Infection Among Colorectal Cancer Patients

2021-09-13

Abstract excerpt

<h4>Background: </h4> The infection of host cells by SARS-CoV-2 is mediated by ACE2 and its co-factors, including TMPRSS2 and FURIN . Patients with cancer are highly susceptible to COVID-19 and exhibit a higher risk of severe progression. However, the mechanism of SARS-CoV-2 infection on colorectal cancer prognosis is largely unknown. Here, we investigated the role of key genes related to SARS-CoV-2 in colorectal...

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Literature Corpus work: b5c506b2-4e63-5c16-b988-663c827cdffa
DOI: 10.21203/rs.3.rs-868323/v1

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