Article

Targeted Gene Bisulfite Sequencing Identifies Differential Methylation in <i>p21</i>

2018-03-29

Abstract excerpt

Next-generation sequencing (NGS) methods are widely available to assess methylation of whole-genomes, reduced representation of genomes, and target capture of many loci, but simple, flexible, and low-cost methods are needed to leverage NGS for sequencing single-locus amplicons from large numbers of samples. We developed a two-stage PCR approach, targeted gene bisulfite sequencing (TGBS) which uses the Illumina MiS...

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Literature Corpus work: df23c3db-f2b1-5103-b77c-1ac6def0a775
DOI: 10.1101/291732

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